PPE_MPTR genes are differentially expressed by Mycobacterium tuberculosis in vivo

S Soldini, I Palucci, A Zumbo, M Sali, F Ria… - Tuberculosis, 2011 - Elsevier
The PPE_MPTR protein sub-family is unique to mycobacteria and comprises proteins found
only in MTB complex and in few other pathogenic mycobacteria. Very little is known about
the precise function of PPE_MPTR, as well as on the expression pattern and the
transcriptional regulation of their structural genes. In the present work, real time RT-PCR
techniques were used to determine the expression profile of PPE_MPTR genes of
Mycobacterium tuberculosis during infection in vivo and in different culture conditions. The …