Transthoracic echocardiography in mice
JL Respress, XHT Wehrens - JoVE (Journal of Visualized Experiments), 2010 - jove.com
In recent years, murine models have become the primary avenue for studying the molecular
mechanisms of cardiac dysfunction resulting from changes in gene expression. Transgenic
and gene targeting methods can be used to generate mice with altered cardiac size and
function, 1-3 and as a result, in vivo techniques are needed to evaluate their cardiac
phenotype. Transthoracic echocardiography, pulse wave Doppler (PWD), and tissue
Doppler imaging (TDI) can be used to provide dimensional measurements of the mouse …
mechanisms of cardiac dysfunction resulting from changes in gene expression. Transgenic
and gene targeting methods can be used to generate mice with altered cardiac size and
function, 1-3 and as a result, in vivo techniques are needed to evaluate their cardiac
phenotype. Transthoracic echocardiography, pulse wave Doppler (PWD), and tissue
Doppler imaging (TDI) can be used to provide dimensional measurements of the mouse …
