New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk
S Kersten - Current opinion in lipidology, 2019 - journals.lww.com
Current opinion in lipidology, 2019•journals.lww.com
Summary ANGPTL3/ANGPTL8 and ANGPTL4 together assure the appropriate distribution of
plasma triglycerides across tissues during different physiological conditions. Large-scale
genetic studies provide strong rationale for continued research efforts to pharmacologically
inactivate ANGPTL3 and possibly ANGPTL4 to reduce plasma lipids and coronary artery
disease risk.
plasma triglycerides across tissues during different physiological conditions. Large-scale
genetic studies provide strong rationale for continued research efforts to pharmacologically
inactivate ANGPTL3 and possibly ANGPTL4 to reduce plasma lipids and coronary artery
disease risk.
Summary
ANGPTL3/ANGPTL8 and ANGPTL4 together assure the appropriate distribution of plasma triglycerides across tissues during different physiological conditions. Large-scale genetic studies provide strong rationale for continued research efforts to pharmacologically inactivate ANGPTL3 and possibly ANGPTL4 to reduce plasma lipids and coronary artery disease risk.
Lippincott Williams & Wilkins