Early determinants of type-2 diabetes

LM Berends, SE Ozanne - Best practice & research Clinical endocrinology …, 2012 - Elsevier
The global prevalence of type-2 diabetes (T2D) has more than doubled in the last 30 years
and is predicted to continue to rise at an alarming rate. The associated health and financial
burdens are considerable. The aetiology of common forms of T2D is multifactorial and
involves a complex interplay between genetic, epigenetic and environmental factors. The
influential role of the environment, in particular our diet and sedentary lifestyles, in diabetes
risk is well established. Of major concern is the increasing prevalence of early onset T2D or …