Recurrent episodes of coma: an unusual phenotype of familial hemiplegic migraine with linkage to chromosome 1
Neuropediatrics, 1999•thieme-connect.com
Over a period of ten years, a boy had several episodes of coma, lasting three to five days.
Each episode was preceded by hemiparesis or paresthesias, aphasia, headaches and
behavioural changes, with subsequent loss of consciousness. Partial seizures occurred
during the first episode. A history of migraine or hemiplegic migraine was found in several
members of the family. Linkage to chromosome 1q21-23, where a gene for familial
hemiplegic migraine has been mapped, was shown in this family.
Each episode was preceded by hemiparesis or paresthesias, aphasia, headaches and
behavioural changes, with subsequent loss of consciousness. Partial seizures occurred
during the first episode. A history of migraine or hemiplegic migraine was found in several
members of the family. Linkage to chromosome 1q21-23, where a gene for familial
hemiplegic migraine has been mapped, was shown in this family.
Abstract
Over a period of ten years, a boy had several episodes of coma, lasting three to five days. Each episode was preceded by hemiparesis or paresthesias, aphasia, headaches and behavioural changes, with subsequent loss of consciousness. Partial seizures occurred during the first episode. A history of migraine or hemiplegic migraine was found in several members of the family. Linkage to chromosome 1q21-23, where a gene for familial hemiplegic migraine has been mapped, was shown in this family.
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