[HTML][HTML] Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino
H Takanaga, B Mackenzie, Y Suzuki… - Journal of Biological …, 2005 - ASBMB
Amino acid homeostasis depends on specific amino acid transport systems, many of which
have been characterized at the molecular level. However, the classical System IMINO,
defined as the Na+-dependent proline transport activity that escapes inhibition by alanine,
had not been identified at the molecular level. We report here the functional characteristics
and tissue distribution of Sodium/Imino-acid Transporter 1 (SIT1), which exhibits the
properties of classical System IMINO. SIT1, the product of the slc6a20 gene, is a member of …
have been characterized at the molecular level. However, the classical System IMINO,
defined as the Na+-dependent proline transport activity that escapes inhibition by alanine,
had not been identified at the molecular level. We report here the functional characteristics
and tissue distribution of Sodium/Imino-acid Transporter 1 (SIT1), which exhibits the
properties of classical System IMINO. SIT1, the product of the slc6a20 gene, is a member of …
