Iminoaciduria: a benign renal tubular defect
PG Procopis, B Turner - The Journal of Pediatrics, 1971 - Elsevier
PG Procopis, B Turner
The Journal of Pediatrics, 1971•ElsevierEscessive excretion of proline, hydroxyproline, and glycine (iminoglycinuria) wasfound in
170 of 200,000 healthy infants screened for aminoaciduria at approximately 7 weeks of age.
Iminoglycinuria persisted in 15 children whereas in 22 a persistent hyperglycinuria
developed. Apart from the finding of moderate hypertension in one child, no clinical
abnormality was present in these children. The heterozygote may be detected by the
presence of hyperglycinuria but this does not always occur.
170 of 200,000 healthy infants screened for aminoaciduria at approximately 7 weeks of age.
Iminoglycinuria persisted in 15 children whereas in 22 a persistent hyperglycinuria
developed. Apart from the finding of moderate hypertension in one child, no clinical
abnormality was present in these children. The heterozygote may be detected by the
presence of hyperglycinuria but this does not always occur.
Escessive excretion of proline, hydroxyproline, and glycine (iminoglycinuria) wasfound in 170 of 200,000 healthy infants screened for aminoaciduria at approximately 7 weeks of age. Iminoglycinuria persisted in 15 children whereas in 22 a persistent hyperglycinuria developed. Apart from the finding of moderate hypertension in one child, no clinical abnormality was present in these children. The heterozygote may be detected by the presence of hyperglycinuria but this does not always occur.
Elsevier
