Modulation of vascular smooth muscle signaling by reactive oxygen species
AN Lyle, KK Griendling - Physiology, 2006 - journals.physiology.org
Physiology, 2006•journals.physiology.org
Modulation of signaling in vascular cells by reactive oxygen species (ROS) affects many
aspects of cellular function, including growth, migration, and contraction. NADPH oxidases,
important sources of ROS, regulate many growth-specific and migration-related signaling
pathways. Identifying the precise intracellular targets of ROS enhances understanding of
their role in cardiovascular physiology and pathophysiology.
aspects of cellular function, including growth, migration, and contraction. NADPH oxidases,
important sources of ROS, regulate many growth-specific and migration-related signaling
pathways. Identifying the precise intracellular targets of ROS enhances understanding of
their role in cardiovascular physiology and pathophysiology.
Modulation of signaling in vascular cells by reactive oxygen species (ROS) affects many aspects of cellular function, including growth, migration, and contraction. NADPH oxidases, important sources of ROS, regulate many growth-specific and migration-related signaling pathways. Identifying the precise intracellular targets of ROS enhances understanding of their role in cardiovascular physiology and pathophysiology.
American Physiological Society