Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin
T Kurki, L Viinikka, O Ylikorkala - American Journal of Obstetrics and …, 1992 - Elsevier
Objective: We studied the role of smooth muscle-relaxing prostacyclin and its endogenous
antagonist, thromboxane A 2, in preterm labor by assessing the urinary output of the
breakdown products of prostacyclin (6-keto-prostaglandin F 1α and 2, 3-dinor-6-keto-
prostaglandin F 1α) and those of thromboxane A 2 (thromboxane B2, 2, 3-dinor-
thromboxane B2). Study Design: Thirty-three women in preterm labor between 25 and 34
weeks of gestation were studied before, during, and after treatment with indomethacin (n …
antagonist, thromboxane A 2, in preterm labor by assessing the urinary output of the
breakdown products of prostacyclin (6-keto-prostaglandin F 1α and 2, 3-dinor-6-keto-
prostaglandin F 1α) and those of thromboxane A 2 (thromboxane B2, 2, 3-dinor-
thromboxane B2). Study Design: Thirty-three women in preterm labor between 25 and 34
weeks of gestation were studied before, during, and after treatment with indomethacin (n …
