Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets
JE Tateson, S Moncada, JR Vane - Prostaglandins, 1977 - Elsevier
Prostacyclin (PGX) strikingly increases cyclic AMP concentrations in human platelets.
Prostacyclin is approximately 10 times more active than PGD 2, 30 times more active than
PGE 1 and more than 1000 times more active than its stable end product, 6-oxo-PGF 1α.
These results correlate well with the anti-aggregating activity of prostacyclin, compared with
PGE 1 and PGD 2.
Prostacyclin is approximately 10 times more active than PGD 2, 30 times more active than
PGE 1 and more than 1000 times more active than its stable end product, 6-oxo-PGF 1α.
These results correlate well with the anti-aggregating activity of prostacyclin, compared with
PGE 1 and PGD 2.
