The receptors and cells for mammalian taste

J Chandrashekar, MA Hoon, NJP Ryba, CS Zuker - Nature, 2006 - nature.com
Nature, 2006nature.com
The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to
what was generally believed, it is now clear that distinct cell types expressing unique
receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and
umami. Importantly, receptor cells for each taste quality function as dedicated sensors wired
to elicit stereotypic responses.
Abstract
The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to what was generally believed, it is now clear that distinct cell types expressing unique receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and umami. Importantly, receptor cells for each taste quality function as dedicated sensors wired to elicit stereotypic responses.
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