Cathepsin expression during skeletal development
M Söderström, H Salminen, V Glumoff… - … et Biophysica Acta (BBA …, 1999 - Elsevier
Cysteine proteinases, cathepsins B, H, K, L and S, have been implicated in several
proteolytic processes during development, growth, remodeling and aging, as well as in a
variety of pathological processes. For systematic analysis of cathepsin gene expression we
have produced cDNA clones for mouse and human cysteine cathepsins. Northern analysis
of a panel of total RNAs isolated from 16–19 different human and mouse tissues revealed
the presence of mRNAs for cathepsin B, H, K, L and S in most tissues, but each with a …
proteolytic processes during development, growth, remodeling and aging, as well as in a
variety of pathological processes. For systematic analysis of cathepsin gene expression we
have produced cDNA clones for mouse and human cysteine cathepsins. Northern analysis
of a panel of total RNAs isolated from 16–19 different human and mouse tissues revealed
the presence of mRNAs for cathepsin B, H, K, L and S in most tissues, but each with a …
