Monitoring HIV-1 treatment in immune-cell subsets with ultrasensitive fluorescence-in-situ hybridisation
BK Patterson, MA Czerniewski, J Pottage, M Agnoli… - The Lancet, 1999 - thelancet.com
BK Patterson, MA Czerniewski, J Pottage, M Agnoli, H Kessler, A Landay
The Lancet, 1999•thelancet.comA: Red symbols are progressive familial intrahepatic cholestasis and homozygous for
1712delT MDR3 mutation; a two-colour symbol is heterozygosity; all green shows women
with intrahepatic cholestasis of pregnancy; yellow symbols show unaffected individuals;
dotted line shows consanguinity of unprecise degree; asterisk shows DNA sequence
analysis was done. B: Wild-type homozygous sequence shows a T at nucleotide 1712,
which is missing on both alleles in homozygous mutation. Heterozygous sequence is …
1712delT MDR3 mutation; a two-colour symbol is heterozygosity; all green shows women
with intrahepatic cholestasis of pregnancy; yellow symbols show unaffected individuals;
dotted line shows consanguinity of unprecise degree; asterisk shows DNA sequence
analysis was done. B: Wild-type homozygous sequence shows a T at nucleotide 1712,
which is missing on both alleles in homozygous mutation. Heterozygous sequence is …
A: Red symbols are progressive familial intrahepatic cholestasis and homozygous for 1712delT MDR3 mutation; a two-colour symbol is heterozygosity; all green shows women with intrahepatic cholestasis of pregnancy; yellow symbols show unaffected individuals; dotted line shows consanguinity of unprecise degree; asterisk shows DNA sequence analysis was done. B: Wild-type homozygous sequence shows a T at nucleotide 1712, which is missing on both alleles in homozygous mutation. Heterozygous sequence is characterised by presence of normal and mutated allele sequences.
thelancet.com
